Culture media with biofluids
The new set of culture media with biofluids for bovine has a series of significant advantages compared to the currently marketed media, due to its innovative formulation and its novel presentation format.
Firstly, its innovative formulation based on natural biofluids (follicular, oviductal, and uterine) whose supplementation in culture media has shown beneficial effects on the development, viability, quality, cryotolerance, and gene expression of bovine embryos (Lopera-Vasquez et al., 2017; Sena-Lopes et al., 2019).
In this regard, it is important to highlight that despite the promising results shown, there are currently no bovine culture media, nor for other mammals, formulated from high-value natural biofluids available in the market.
The use of these biofluids will eliminate the need for using serum and other supplements that have been shown to have a detrimental effect on mitochondrial activity and in vitro development of bovine oocytes (Restrepo et al., 2007).
This new formulation will enable better replication of the natural conditions of the reproductive tract, substantially reducing embryonic stress during in vitro culture, mitigating possible embryo alterations during its development, improving biological safety, and genetic and epigenetic quality.
As a result, embryos more similar to those produced live will be obtained, thereby enhancing the outcomes of assisted reproduction techniques in the bovine species.